31st October 2025 Newsletter
Hi guys. This is the tenth newsletter from the Rejuvenation Science Institute (ICR). In these newsletters, we will tell you what we've done, since the last newsletter, to accelerate the development of rejuvenation science.
ICR attends the São Paulo Longevity Forum
The president of the Rejuvenation Science Institute (ICR), Nicolás Cherñavsky, attended the São Paulo Longevity Forum at the end of October, which is the largest event dedicated to aging, longevity and rejuvenation in Brazil. He attended only as a congressman, to watch the presentations, but it was also an important networking opportunity to establish relationships with important people in the field in Brazil, both in the public and private sectors. In addition — as discussed with the event organizer on that occasion — with the completion of the rat rejuvenation experiment, it is possible that in future editions we will participate in the forum presenting the experiment and its results — which, if all goes well, will be the confirmation of the invention of mammalian rejuvenation.
Seven months to go to the start of a dream
In May 2020, the Rejuvenation Science Institute did not yet exist. We — Nicolás and Nina — were a little tired of the lack of progress in rejuvenation science in previous years. Although there were many initiatives in the field, there were few results. In addition, the scientific theoretical foundations of the main currents in the field were not sufficiently convincing — which, incidentally, was consistent with the lack of concrete results. Something had to happen. And it did.
On May 11th, 2020, Steve Horvath published a scientific article reporting 54% of epigenetic rejuvenation in rats in an experiment coordinated by Harold Katcher. If this result could be reproduced openly and transparently, it could be confirmed, and then a giant step would have been taken toward human rejuvenation. After more than five years, that moment is approaching. There are only seven months left until the start of the experiment to rejuvenate rats with Pig Plasma Extracellular Particles (PPEPs) from young animals, because in May 2026 we will begin collecting blood from young pigs, and the following month we will inject the PPEPs into rats to rejuvenate them.
However, we have not yet raised all the funds needed to complete the experiment. We still need to raise 26.44% of the total, even though we have already raised $55,168 (we still need the raise $19,832). Thanks to 39 contributors — some who contributed with larger amounts, such as DoNotAge.org and Heales, and others who contributed with $3 — we have made it this far, but in the last seven months before the experiment, we need to raise the full amount in order to complete the experiment, not just start it.
We recently reached 100 subscribers to this newsletter. We see this experiment as a collective effort, and now more than ever we need your help. You can certainly spread the word to the rejuvenation community that there are seven months left until the experiment and we need to complete its funding. For us, conducting this experiment is a dream coming true, as we will finally know whether rejuvenation has been invented or not. However, we believe that although thousands of people share this desire, many may not be aware of our experiment. Therefore, we are counting on you to inform everyone who dreams of the invention of rejuvenation about our experiment, so that it can cease to be a dream and become a reality.
In two days, 2nd of November, we will be interviewed at the Virtual Enlightenment Salon
There are only two days left until our interview (with Nicolás and Nina) at the Virtual Enlightenment Salon, hosted by Gennady Stolyarov and other participants. Stolyarov is the chairman of the United States Transhumanist Party, and he regularly carries out conversations with relevant people from the rejuvenation field. The interview will start at 1 pm (US Pacific Time) and will be broadcast live on YouTube, allowing viewers to participate in a live chat and ask us questions. We are very happy to participate in this event, since Stolyarov is a longstanding participant of the rejuvenation field, and the salons are traditionally a place where rejuvenation science can be discussed in depth with a very knowledgeable public. You can watch the playlist of the Enlightenment Salons by clicking here.
Raised funds reach 73.56% of the total
By the end of October 2025, the ICR has already raised 73.56% of the total needed to carry out the experiment to rejuvenate rats with PPEPs. This brings the total raised to US$ 55,168, with the remaining 26.44% still to be raised to reach the total of US$ 75,000. The ICR is contacting as many players in the field of rejuvenation science as possible to inform them about the experiment and the possibility of donations. In addition, we are looking for specialized media that may be interested in publicizing our initiative. So, if you know of a YouTube channel, podcast, newspaper or other media outlet that might be interested in publicizing this experiment, feel free to talk to us about it or directly to the media outlet.
This is a collective effort
This experiment is a collective effort to reproduce Harold Katcher's seminal study, in which the ICR relies on the contribution of those interested in the realization of the experiment. Thus, if you know someone who might be interested in the content of this newsletter, you can forward it to them. Also, if you are not yet a financial contributor of the ICR, we invite you to become one by clicking on this link.
So that's it. We're carrying on, and we won't rest until we've implemented rejuvenation in human beings. See you next time!