30th September 2025 Newsletter
Hi guys. This is the ninth newsletter from the Institute of Rejuvenation Science (ICR). In these newsletters, we will tell you what we've done, since the last newsletter, to accelerate the development of rejuvenation science.
What is Harold Katcher’s plasma fraction?
In this video, Nina Torres Zanvettor, vice-president of the Rejuvenation Science Institute (ICR), explains what the plasma fraction by Harold Katcher actually is. This plasma fraction was used by the researcher to achieve the best result in the history of mammalian rejuvenation science. Nina, who has a master's degree in Inorganic Chemistry from the university Unicamp, with a focus on medicinal bioinorganic chemistry, explains what Katcher's article in Geroscience published in 2023 tells us about the composition of his plasma fraction and why the ICR, together with the university Unicamp, decided to reproduce the experiment to verify a result that could change the fundamental paradigms of rejuvenation science. Click here to watch the video.
We will be interviewed in theVirtual Enlightenment Salon on November 2 at 1 p.m. U.S. Pacific Time
We, Nicolás and Nina, will be interviewed by Gennady Stolyarov and other participants in the Virtual Enlightenment Salon on November 2nd. Stolyarov is the chairman of the United States Transhumanist Party, and he regularly carries out conversations with relevant people from the rejuvenation field. The interview will start at 1 pm (US Pacific Time) and will be broadcast live on YouTube, allowing viewers to participate in a live chat and ask us questions. We are very happy to participate in this event, since Stolyarov is a longstanding participant of the rejuvenation field, and the salons are traditionally a place where rejuvenation science can be discussed in dept with a very knowledgeable public. You can watch the playlist of the Enlightenment Salons by clicking here.
Raised funds reach 72.63% of the total
By the end of September 2025, the ICR has already raised 72.63% of the total needed to carry out the experiment to rejuvenate rats with PPEPs. This brings the total raised to US$ 54,473, with the remaining 27.37% still to be raised to reach the total of US$ 75,000. The ICR is contacting as many players in the field of rejuvenation science as possible to inform them about the experiment and the possibility of donations. In addition, we are looking for specialized media that may be interested in publicizing our initiative. So, if you know of a YouTube channel, podcast, newspaper or other media outlet that might be interested in publicizing this experiment, feel free to talk to us about it or directly to the media outlet.
Regular lives on Instagram in Spanish: Nicolás talks to the Chilean influencer Sergio Schilling
Starting some weeks ago, the president of the Rejuvenation Science Institute (ICR), Nicolás Cherñavsky, has been regularly participating in livestreams with the Chilean influencer Sergio Schilling to discuss rejuvenation science, the rats’ rejuvenation experiment, and the social and psychological consequences not only of human rejuvenation, but also of the existence of aging. In these conversations, carried out in Spanish, Nicolás and Sergio explore the desire for freedom that rejuvenation actually means, allowing us to break free from the restrictions that biology imposes on us in all the steps of the biological path through life. To watch the latest conversation click here.
Article: The rats that could go down in history
Sprague Dawley rats that will participate in the experiment at the animal facility of the Institute of Biology at the university Unicamp.
We are used to following scientific experiments involving rats and mice. Very often, they are sacrificed during or at the end of the experiment, rather than dying a natural death. In the rat rejuvenation experiment to be conducted by the Rejuvenation Science Institute (ICR) in collaboration with the university Unicamp, the group of 10 treated old rats will receive a potentially rejuvenating therapy of Pig Plasma Extracellular Particles (PPEPs), and if they do indeed rejuvenate, they will be kept alive, receiving a periodic dose of the therapy.
How long will they remain alive? That is what we will find out in practice. Who knows, maybe they will stay young forever, living forever? The other group of 10 old rats, which will be the old control group, will not receive the rejuvenating therapy, but if the treatment with PPEPs does indeed rejuvenate the treated rats, these control rats will also remain alive until they die of natural causes.
As for the young rats in the experiment, the group of 10 treated young rats will receive the PPEPs therapy to potentially remain young as long as possible, also receiving the therapy periodically. The group of 10 young control rats will not receive the PEPPs therapy, but will also live until they die naturally if the treatment rejuvenates the treated rats.
This is a collective effort
This experiment is a collective effort to reproduce Harold Katcher's seminal study, in which the ICR relies on the contribution of those interested in the realization of the experiment. Thus, if you know someone who might be interested in the content of this newsletter, you can forward it to them. Also, if you are not yet a financial contributor of the ICR, we invite you to become one by clicking on this link.
So that's it. We're carrying on, and we won't rest until we've implemented rejuvenation in human beings. See you next time!