30th April Newsletter
Hi guys. This is the fourth newsletter from the Institute of Rejuvenation Science (ICR). In these newsletters, we will tell you what we've done, since the last newsletter, to accelerate the development of rejuvenation science.
Proceedings with Unicamp have officially begun
At the end of April 2025, the proceedings for the agreement between the Rejuvenation Science Institute (ICR) and the University of Campinas (Unicamp), a university located in the same city as the ICR (Campinas/Brazil), finally got started. According to the documentation of the agreement, the ICR and Unicamp will jointly carry out the experiment of rejuvenating rats with PPEPs (Pig Plasma Extracellular Particles), at the university's Institute of Biology. This experiment is an attempt to reproduce the results obtained by Harold Katcher, described in his scientific article in the journal Geroscience. On Unicamp's side, Professor Marcelo Mori, a world-class scientist specializing in aging, will be in charge, bringing the highest possible technical quality to this experiment, which aims to verify whether or not the rejuvenation of mammals has been achieved. The agreement is expected to take a few months to be processed and will possibly be completed at the beginning of the second half of 2025.
Visit to the pig farm
In mid-April 2025, we personally met a pig farmer from a town near ours and visited his pig farm. We managed to close a deal in which we will collect the blood of 10 pigs slaughtered by this farmer. In the experiment to rejuvenate rats with PPEPs, we will need the blood of these 10 young pigs to isolate the PPEPs. Therefore, in April and May 2026, the ICR will collect this blood and transport it to Unicamp where the laboratory steps for isolating the PPEPs will be carried out. The pigs will be raised free-ranging and on a healthy diet, and slaughter and blood collection will take place when they are 7 months old. Thus, the stage of selecting the farm to collect the pigs' blood was successfully completed.
Raised funds reach 53% of the total
During the month of April 2025, the ICR received an important part of the funds to be donated by DoNotAge.org, with the rest arriving in May and June. In total, DoNotAge.org is donating US$25,000 to the experiment, in addition to the US$10,000 already donated by Heales. In addition, new and old donors of smaller amounts have contributed to reaching 53.14% of the total financial resources needed to carry out the experiment. If you are not yet a donor and would like to contribute, you can do so by clicking here.
The rats are already at the Institute of Biology
The 20 old rats that will be involved in the study are already at Unicamp's Institute of Biology (IB). The feed and wood shavings have already been purchased, and the animals are between 11 and 12 months old, bearing in mind that we need to wait for them to reach the age of 25 months before they receive the PPEPs injections in June 2026. The rats are being cared for by veterinarian Leandro Cardoso, from Unicamp's Institute of Biology, a long-time collaborator of Professor Marcelo Mori.
Video by our president Nicolás Cherñavsky
A scientific article published a few days ago is the subject of a video by ICR president Nicolás Cherñavsky. The article analyzed in this video, published on the ICR's YouTube channel, shows that there are a number of published scientific experiments that indicate that small extracellular vesicles of young origin are extremely promising when it comes to reversing aging. The article, which has the participation of great exponents of the science of rejuvenation, such as Vadim E. Fraifeld and Vera Gorbunova, deserves the attention of all those who trust science to save the lives of the billions of people who suffer from aging and its associated diseases. You can watch the video by clicking here, and read the article here. It is worth remembering that in addition to YouTube, the ICR publishes content and updates on two other social networks, Instagram and LinkedIn.
This is a collective effort
This experiment is a collective effort to reproduce Harold Katcher's seminal study, in which the ICR relies on the contribution of those interested in the realization of the experiment. Thus, if you know someone who might be interested in the content of this newsletter, you can forward it to them. Also, if you are not yet a financial contributor of the ICR, we invite you to become one by clicking on this link.
So that's it. We're carrying on, and we won't rest until we've implemented rejuvenation in human beings. See you next time!